Professor Ruoling Chen

Image of Professor Ruoling Chen

Professor Ruoling Chen CV

Qualifications: MBChB, MSc (Med Stats), PhD (Epid), Fellow of the Royal Society of Medicine

Role: Lead of Global Health and Epidemiology

Prof Ruoling Chen is Professor of Public Health and Medical Statistics and Lead of Global Health and Epidemiology research at the University of Wolverhampton.   He obtained his PhD at the University of Aberdeen in 1997, after studying medicine (MB) and a 3-year full-time postgraduate course for medical statistics (MSc) in China. Before joining the University as a Reader in 2009 Dr Chen worked at the Universities of Liverpool, Dundee and London as a lecturer and senior lecturer in medical statistics and epidemiology for 14 years. He worked as a research associate at INSERM U444 and Universite Paris VII, France during one year of 1992-1993 on the methodology of meta-analysis in occupational epidemiology, following several years of teaching and junior doctor posts in a medical university and hospital in China.

Prof Chen is an international expert on public health and epidemiology. He worked on the MRC-ALPHA study for mental health in older people in Liverpool, the Scottish Heart Health Study and the Myocardial Infarction National Audit Project, England & Wales. Prof has established a large-scale population-based cohort study of dementia and other chronic disease in older people in six provinces in China. His research interests include Aging and Chronic Diseases, Social Medicine and Clinical Epidemiology. As a principal investigator, Prof Chen has led and conducted a number of national and international research projects in public health and epidemiology, supported by UK grants (eg, the BUPA Foundation, Alzheimer’s Research).  He has national and international research collaborations, including from University College London, King’s College London and Neuroscience Research Australia/University of New South Wales (Prof Kaarin Anesty). Prof Chen has been often invited to give research seminar talks by medical universities in China ( He has had a wide network linked with medical universities in China, helping the University of Wolverhampton for collaborative research and teaching programmes ( He has been often invited to give seminar

Currently, Prof Ruoling Chen leads a research group in global health and epidemiology. The group consists of post-doctoral researchers and senior academic staff, and provides several places for future PhD candidates to work on important topics in public health and care. It also provides expertise and advice for staff on health data analyses, clinical epidemiology and population-based health research.

On-going PhD Research Projects

PhD student

Study Topic


Aishae Bakre

Dietary intakes and dementia risk

Ruoling Chen,

Angela Clifford

Isaac M Danat

Determinants and health effects of body weight in older People

Ruoling Chen, Linda Lang

Weiju Zhou

Risk factors and outcomes of coronary heart disease and stroke in older Chinese

Ruoling Chen,

Alexandra Hopkins, Angela Clifford

Rizwan Nazim

Passive smoking, oral health and dementia

Ruoling Chen,

Marin Partridge

Dr Yuhui Wan (Associate Professor, School of Public Health, Anhui Medical University, China) is a visiting scholar, carrying out research on health inequality in Chinese population including adolescents through examining large-scale health survey datasets.  

Major Research Grant (PI)

Association of dementia with indoor and outdoor air pollution, funded by European Commission Horizon 2020 Framework Programme (H2020-MSCA-IF-2016/2017) (£300,608) (2018-2020)

 Risk factors, health care and outcomes of dementia in people who are socio-economically deprived but at high level of social support and low level of depression, funded by the BUPA Foundation, UK (£254,000) (2008-2013)

External Academic and Research Activities

Associate Editor, BMC Public Health  (2011-)

Editorial Board, The Psychiatric Bulletin  (2014-)

Editorial Board, World Journal of Psychiatry  (2011-)

Peer Reviewing

Scientific journals, eg,  New England Medical Journal, Lancet, British Medical Journal, Int J Epidemiol, Am J Epidemiol, Br J Psychiatry, J Neurol Neurosurg Psychiatry, Stroke.

Grant awarding bodies, eg, National Institute for Health Research, England (Programme Grant and RfPB Grant), UK MRC Joint Health Systems Research Initiative, European Commission Horizon 2020 (Heath and Ageing. Unit E.4).

Selected Publications

1                    Bakre AT, Chen R (correspondent), Khutan R, Wei L, Smith T, Qin G, Danat IM, Zhou W, Schofield P, Clifford A, Wang J, Verma A, Zhang C, Ni J. Association between fish consumption and risk of dementia: a new study from China and a systematic literature review and meta-analysis. Public Health Nutr. 2018 Mar 19:1-12. doi: 0.1017/S136898001800037X.

2                    Anstey KJ, Chen R. Invited Commentary: Second-hand smoke is an under recognized risk factor for cognitive decline. Am J Epidemiol. 2018 Jan 12. doi: 10.1093/aje/kwx378.

3                    Lang L, Clifford A, Wei L,  Zhang DM, Leung D, Augustine G, Copeland JMR, Anstey KJ,  Chen R.Prevalence and determinants of undetected dementia in the community: a systematic literature review and a meta-analysis”. BMJ open 2017;7:e011146.

4                    Pan Y, Chen R (correspondent), Li Z, Li H, Zhao X, Liu L, Wang C, Wang Y, Wang Y. Socioeconomic status and the quality of acute stroke care: the China National Stroke Registry. Stroke 2016;47:2836-42.

5                    Chen R, Lang L, Clifford A, Chen Y, Hu Z, Han TS. Demographic and socio-economic influences on community-based care and caregivers of people with dementia in China. Journal of the Royal Society of Medicine Cardiovascular Disease 2016;5:1–15.

6                    Li YT, Wang HH, Liu KQ, Lee GK, Chan WM, Griffiths SM, Chen R. Medication adherence and blood pressure control among hypertensive patients with coexisting long-term conditions in primary care settings. Medicine (Baltimore)  See comment in PubMed Commons below2016;95:e3572

7                    Clifford A, Lang L,Chen R (correspondent), Anstey KJ, Seaton A. Exposure to Air Pollution and Cognitive Functioning across the Life Course – a systematic literature review.  Environmental Research 2016;147: 383-98

8                    McCormick J, Chen R. Impact of socioeconomic deprivation on mortality in people with haemorrhagic stroke: a population-based cohort study. Postgrad Med J 2016;92:501-5

9                    Pang YS, Song T, Chen R (correspondent), Li H, Zhao XQ, et al. Socioeconomic deprivation and mortality in people after ischemic stroke: the China National Stroke Registry. Int J Stroke 2016;11:557-64.

10                Chen R,Crichton SL, McKevitt CJ, Rudd AG, Sheldenkar A, Wolfe CDA. Association between Socioeconomic Deprivation and Functional Impairment after Stroke: the South London Stroke Register.  Stroke 2015; 46:800-5.

11                Hu Z, Zaman MJ, Wang J, Peacock JL, Chen R. Correlates of Untreated Hypercholesterolemia in Older Adults: A Community-Based Household Survey in China. PLoS One. 2015;10:e0131318.

12                Chen R,Hu Z, Chen RL, Zhang D, Xu L, Wang J, et al. Socioeconomic deprivation and survival after stroke in China: a systematic literature review and a new population-based cohort study. BMJ Open. 2015;5:e005688.

13                Birkhead J, Weston C, Timmis A, Chen R. The effects of intravenous insulin infusions on early mortality for patients with acute coronary syndromes who present with hyperglycaemia; a matched propensity analysis using data from the MINAP database 2008-2012. European Heart Journal: Acute Cardiovascular Care 2014; pii: 2048872614549733.

14                Chen R, McKevitt CJ, Rudd AG, Wolfe CDA. Socioeconomic Deprivation and Survival after Stroke: Findings from the Prospective South London Stroke Register of 1995-2011. Stroke 2014; 45: 217-23.

15                Greaves K, Chen Y, Appadurai V, Hu Z, Schofield P, Chen R. The prevalence of doctor-diagnosed angina in 4314 older adults in China and comparison with the Rose angina questionnaire: the 4 province study. Int J Cardiology. 2014;177:627-8.

16                Chen R, McKevitt CJ, Crichton SL, Rudd AG, Wolfe CDA. Socioeconomic deprivation and provision of acute and long-term care after stroke: the South London Stroke Register cohort study. Journal of Neurology, Neurosurgery & Psychiatry 2014; 85:1294-300.

17                Sheldenkar A, Crichton S, Douiri A, Rudd AG, Wolfe CD, Chen R. Temporal trends in health-related quality of life after stroke: analysis from the South London Stroke Register 1995-2011. Int J Stroke 2014; 9:721-7.

18                Chen R,  Hu Z, Chen LR, Ma Y, Zhang DM, Wilson K. Determinants for undetected dementia and depression in older adults. Br J Psychiatry 2013;203:203-8.

19                Zhang D, Hu Z, Orton S, Wang JJ, Zheng J, Qin X, Chen R. Socioeconomic and psychosocial determinants of smoking and passive smoking in older adults. Biomed Environ Sci 2013;26:465-470.

20                Chen R, Wilson K, Chen Y, Zhang D, Qin X, He MZ, Hu Z, Ma Y, Copeland JR. Association between environmental tobacco smoke exposure and dementia syndromes.Occup Environ Med 2013;70: 63-69.

21                Schofield P, Nicola Crichton N, Chen RMethods for assessing cardiovascular disease risk in a UK black population. Heart 2012;98:1373-7.

22                Chen R. Association of environmental tobacco smoke with dementia and Alzheimer's disease among never smokers. Alzheimer's & Dementia 2012;8:590-5.

23                Clifford A, Lang L, Chen R.  Effects of maternal cigarette smoking during pregnancy on cognitive parameters of children and young adults - a literature review. Neurotoxicol Teratol 2012;34:560-70.

24                Chen R, Zhang D, Chen Y, Hu Z, Wilson K. Passive smoking and risk of cognitive impairment in women who never smoke. Arch Int Med 2012;172:271-3.

25                Chen R, Ma Y, Wilson K, Hu Z, Sallah D, Wang JJ, et al. A multicentre community-based study of dementia cases and subcases in older people in rural and urban China--the GMS-AGECAT prevalence and socio-economic correlates. Int J Geriatr Psychiatry 2012;27:692-702.

26                Lang L, Orton S, Sallah D, Hewitt-Moran T, Zhang D, Cullen S, Dixon S, Bell B, Bell D, Meeson L, Chen R. A survey of engagement and competence levels in interventions and activities in a community mental health workforce in England. BMC Health Serv Res 2011;11:352.

27                Shah AD, Nicholas O, Timmis AD, Feder G, Abrams KR, Chen R, et al. Threshold haemoglobin levels and the prognosis of stable coronary disease: two new cohorts and a systematic review and meta-analysis. PLoS Med; 2011;8:e1000439

28                Henriksson M, Palmer S, Chen R, Damant J, Fitzpatrick N, Abrams K, et al. Assessing the cost effectiveness of using prognostic biomarkers with decision models: case study in prioritising patients waiting for coronary artery surgery. BMJ 2010; 340:b5606

29                Hemingway H, Henriksson M, Chen R, Damant J, Fitzpatrick N, Abrams K, et al. The effectiveness and cost-effectiveness of biomarkers for the prioritisation of patients awaiting coronary revascularisation: a systematic review and decision-model. Health Technol Assess. 2010;14:1-151.

30                Chen R. Mortality attributable to smoking in China. N Engl J Med 2009;360:1911.

31                Birkhead J, Weston C, Chen R. Determinants and outcomes of coronary angiography after non-ST-segment elevation myocardial infarction: a cohort study of the Myocardial Ischemia National Audit Project (MINAP). Heart 2009;95:1593-9.

32                Chen R, Hu Z, Wei L, Qin X, Copeland JRM. Is the relationship between syndromes of depression and dementia temporal? - the MRC-ALPHA and Hefei-China studies. Psychol Med 2009;39:425-30.

33                Hemingway H, Chen R, Junghans C, Timmis A, Black N, Shekelle P, et al. Appropriateness criteria for coronary angiography in angina: reliability and validity. Ann Intern Med 2008;149:221-31.

34                Chen R, Hu Z, Wei L, Qin X, McCracken C, Copeland JRM. Severity of depression and risk for subsequent dementia: cohort studies in China and the UK. Br J Psychiatry 2008;193:373-7.

35                Sekhri N, Timmis A, Chen R, Junghans C, Walsh N, Zaman J, et al. Inequity of access to investigation and effect on clinical outcomes: prognostic study of coronary angiography for suspected stable angina pectoris. BMJ 2008;336:1058-61.

36                Wei L, Chen R, MacDonald TM. Channelling of SSRIs and SNRIs use in the Tayside population, Scotland. Pharmacoepidemiol Drug Saf 2007;16:859-66.

37                Chen R, Kumar S, Timmis A, Feder G, Yaqoob M, Hemingway H. Comparison of the relation between renal impairment, angiographic coronary artery disease and long-term mortality in women vs men. Am J Cardiol 2006;97:630-2.

38                Syme P, Byrne A, Chen R, Devenny R, Forbes J. Community-based stroke incidence and case-fatality in a Scottish population - the Scottish Borders Stroke Study (SBSS). Stroke 2005;36:1837-43.

39                Chen R, Tunstall-Pedoe H. Socioeconomic deprivation and waist circumference in men and women: the Scottish MONICA surveys 1989-95. European J Epidemiol 2005;20:141-7.

40                Chen R, Wei L, Hu Z, Qin X, Copeland JRM, Hemingway H. Depression in older people in rural China. Arch Int Med 2005;165:2019-25.

41                Chen R, Hu Z, Qin X, Xu XC, Copeland JMR. A community-based study of depression in older people in Hefei, China – the GMS-AGECAT prevalence, case validation and socio-economic correlates. Int J Geriatr Psychiatry 2004;19:407-13.

42                Chen R, Tavendale R, Tunstall-Pedoe H. Coronary heart disease in relation to passive smoking by self report, serum cotinine and their combination: Scottish MONICA study. Occup Environ Med 2004; 61:790-2.

43                Chen R, Wei L, Syme P. Comparison of early and delayed respondents to a postal health survey: a questionnaire study of personality traits and neuropsychological symptoms. European J Epidemiol 2003; 18:195-202.

44                Chen R, Tavendale R, Tunstall-Pedoe H. Measurement of passive smoking in adults: self-reported questionnaire or serum cotinine? J Cancer Epidemiol & Prev (formerly J Epidemiol Biostat) 2002; 7:85-95.

45                MacWalter RS, Wong SYS, Wong KYK, Stewart G, Fraser CG, Fraser HW, Ersoy Y, Ogston SA, Chen R. Does renal dysfunction predict mortality after acute stroke? a seven year follow-up study. Stroke 2002;33:1630-35.

46                Chen R, Tunstall-Pedoe H. Cancer risk, hypertension, and antihypertensive medication. Lancet 2002; 359:77.

47                Chen R, Tunstall-Pedoe H, Tavendale R. Environmental tobacco smoke and lung function in employees who never smoked: the Scottish MONICA study. Occup Environ Med 2001;58: 563-8.

48                Chen R, Semple S, Dick F, Seaton A. Nasal, eye and skin irritation in dockyard painters. Occup Environ Med 2001;58: 542-3.

49                Chen R, Dick F, Semple S, Seaton A, Walker LG. Solvent exposure and personality. Occup Environ Med 2001;58:14-8.

50                Chen R, Tunstall-Pedoe H, Bolton-Smith C, Hannah MK, Morrison C. Association of dietary antioxidants and waist circumference with pulmonary function and airway obstruction. Am J Epidemiol 2001;153:157-63.

Book and Chapters

51                Chen R. Cognitive Development: Theories, Stages & Processes and Challenges (Book). Nova Science Publishers, Inc. p.293. New York, USA. 2014. ISBN-10:1631176048. Total pages 293

52                Chen R, Roberts N.Environmental pollution, neurodevelopment and cognitive impairment (Chapter). p.255-277. In the book -  Cognitive Development: Theories, Stages & Processes and Challenges. 2014. Nova Science Publishers, Inc. New York, USA.

53                Chen R, Copeland JRM. Epidemiology of depression in older people: prevalence and incidence (Chapter). p.479-488. In: Abou-Saleh MM, Katona CLE, and Kumar A. (eds): Principles and Practice of Geriatric Psychiatry (3rd Edition). Wiley-Blackwell, West Sussex, UK.  2011. ISBN: 978-0-470-74723-0