Appendix A: Human Tissue and Relevant Material

 

Human Tissue Type

Relevant Material?

Antibodies

No

Bile

Yes

Blood

Yes

Bone marrow

Yes

Bones/skeletons

Yes

Brain

Yes

Breast milk

Yes

Breath condensates and exhaled gases

No

Buffy coat layer (interface layer between plasma and blood cells when blood is separated)

Yes

Cell lines

No

Cells that have divided in culture

No

CSF (cerebrospinal fluid)

Yes

Cystic fluid

Yes

DNA

No

Eggs (ova)*

No

Embryonic stem cells (cells derived from an embryo)

No

Embryos (outside the body)*

No

Extracted material from cells e.g. nucleic acids, cytoplasmic fractions, cell lysates, organelles, proteins, carbohydrates and lipids.

No

Faeces

Yes

Fetal tissue

Yes

Fluid from cystic lesions

Yes

Gametes*

No

Hair (from deceased person)

Yes

Hair (from living person)

No

Joint aspirates

Yes

Lysed cells

No

Mucus

Yes

Nail (from deceased person)

Yes

Nail (from living person)

No

Nasal and bronchial lavage

Yes

Non-blood, derived stem cells (i.e. derived from the body.)

Yes

Non-fetal products of conception ( i.e. the amniotic fluid, umbilical cord, placenta and membranes)

Yes

Organs

Yes

Pericardial fluid

Yes

Plasma (Please note: Depending on how plasma is prepared and processed, it may contain small numbers of platelets and other blood cells. If any of these cells are present, then the plasma must be regarded as relevant material).

No

Platelets

Yes

Pleural fluid

Yes

Primary cell cultures (whole explant/biopsy present)

Yes

Pus

Yes

RNA

No

Saliva

Yes

Sebum

No

Serum

No

Skin

Yes

Sperm cells (spermatozoa)*

No

Sputum (or phlegm)

Yes

Stomach contents

Yes

Sweat

No

Teeth

Yes

Tumour tissue samples

Yes

Umbilical cord blood stem cells

Yes

Urine

Yes

* While outside the definition of relevant material for the purposes of the Human Tissue Act 2004, these materials fall within the remit of the Human Fertilisation and Embryology Act 1990, and are regulated by the Human Fertilisation and Embryology Authority (HFEA). - See more at: https://www.hta.gov.uk/policies/list-materials-considered-be-%E2%80%98relevant-material%E2%80%99-under-human-tissue-act-2004#sthash.YFIofFhV.dpuf