In this module you will acquire the necessary knowledge, skills and understanding of big data acquisition and analysis to gain insight into personalized medicine approaches. In order to achieve this you will attend a series of lectures and workshops covering the theory and practice of multi-omic approaches, as well as other 'state of the art' techniques in generating large data sets along with their analysis. This will provide you with the foundation skills necessary to begin identifying potential biomarkers and therapeutic targets within complex pathophysiological mechanisms that underlie many diseases.
This is a research-based project that provides the opportunity to demonstrate an ability to plan and conduct an independent research investigation related to the overall programme of study. This will involve identification of research aims and objectives based on the literature followed by data collection, critical analysis and interpretation of results in relation to relevant literature.
Students will take a diet of practicals that provide preparation for their later research project work. This skill based laboratory module aims to provide a series of practicals designed to provide students from a variety of backgrounds with appropriate technical skills. The module aims to contribute to the development of communication, organisational and scientific skills.
The module covers, in depth, the key aspects of the molecular basis of disease. Underpinning this will be keynote lectures and tutorials covering: - The mechanism of disease at the cellular level - Cell death - Pathogens and the host response - Hereditary and disease/ inherited disorders - Developmental biology and developmental disorders The Molecular basis of specific diseases will be covered by expert lectures: - The molecular basis of cancer: (Colorectal cancer, Breast Cancer, Brain Cancers) - Developmental disorders such as Polycystic Kidney Disease (PKD) - Diabetes - Virally transmitted diseases Particular emphasis will be placed on cellular pathways and biochemistry of these diseases. Often, keynote lectures will reference original research papers and the scientific method will be discussed. The two assessments (A PowerPoint presentation and a review of an original research paper) will allow the student to demonstrate deep understanding and synthesis of complex ideas within the field.
This module is designed to ensure that the student has a basic understanding of molecular genetics, gene structure and genomics, and then is provided with the opportunity to develop this understanding to a sophisticated level. Techniques of gene manipulation such as sequencing, cloning, PCR, microarrays, transformation and transgenics will be explained. The module is designed to ensure that students have a thorough understanding of the principles of gene manipulation and genomic investigation and how these processes can be used for understanding disease inheritance and diagnosis. This module will involve a tailored report on genome analysis.
This is a module directed at postgraduate students and aims at building skills in project management, technology transfer, fund sourcing for research, setting up collaborations and for developing business enterprise in molecular cell biology.
This is a module directed to postgraduate students which develops tools and methodologies required for advanced research study. This includes project planning, data analysis and choice of statistical packages, time, project and data management, technology transfer and setting up collaborations, data presentation, information retrieval and report writing including selection of methods. This module is designed such that the student builds up a portfolio of expertise, which sets the ground and provides specific information for their research project. This module is designed such that the student can also benefit by undertaking this module in a self-study mode.