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Professor Izabela Radecka

Professor Izabela Radecka

Professor in Biotechnology

  • Email address I.Radecka@wlv.ac.uk
  • Phone number 01902 322366
  • Faculty Faculty of Science and Engineering
  • Institute School of Biology, Chemistry and Forensic Science
  • Areas of expertise

    Biosynthesis of microbial polymers using fermentation processes

    Development of novel bio-based polymeric materials

Iza has an MSc in Biological Sciences from the University of Silesia, Poland completed in 1990. Within biosciences she first specialised in anatomy and histology (interactions between heavy metals and enzymatic activity in brain tissue). In 1991 she took a position as a junior research worker in the Institute of Polymer Chemistry at the Polish Academy of Sciences in Zabrze, Silesia, with a special interest in the biodegradability of different synthetic polymer blends. After one year there she decided to take a PhD researcher/lecturer post at the University of Silesia, Katowice, with a special interest in microbial biotechnology concerning the production of biodegradable polymers by bacteria under different environmental conditions. Iza completed my PhD in the Department of Biochemistry, University of Silesia, Katowice.

Iza joined the School of Applied Sciences at the University of Wolverhampton in September 2000. Since then she has continued her research into the production of biodegradable plastics from bacteria. Her research is focused on the cost-effective production of novel bio-based polymeric materials from waste.  Iza has published numerous research papers in highly ranked scientific journals, authored several chapters in biotechnological books. Iza has also given a broad number of invited lectures at international conferences.

She was awarded a Mercia Spinner Pathfinder concept grant and Enterprise Fellowship Scheme to develop new biopolymer extraction methods from bacteria grown in large fermenters.

Iza teaches on a wide variety of microbiology and biotechnology courses, both undegraduate and postgraduate level where she puts her knowledge and experience to good effect. Iza is also active member of the University of Wolverhampton Antimicrobial Research Development (UWARD) group.

Iza also is a tutor for Erasmus/Socrates exchange students.

  • Application of antimicrobial activity of silver, zinc, strontium and copper
  • Use of wastes for eco-efficient production of high added value products
  • Production of biodegradable polymers by bacteria under different environmental conditions and their applications
  • Probiotics
  • Bioremediation
  • Member of Society of General Microbiology.
  • Member of Royal Society of Chemistry
  • Fellow of the Society of Biology.
  • Member of FoodWasteNet Network.
  • Member of a stakeholder advisory group at DEFRA on the development of biodegradable plastic bag standards.

Publications

 

Selected journal publications:

 

Gupta, A., Kowalczuk, M., Heaselgrave, W., Britland, ST, Martin, C., Radecka, I. (2018) The production and application of hydrogels for wound management: A Review. European Polymer Journal , 111 (2019) 134–151, doi.org/10.1016/j.eurpolymj.2018.12.019

 

Khalil, I., Khechara, M.,   Kurusamy, S., Armesilla, A., Gupta, A., Mendrek, B., Khalaf, T., Scandola, M., Focarete, ML.,  Kowalczuk, M and  Radecka, I.  (2018) Poly-Gamma-Glutamic Acid (γ-PGA)-Based Encapsulation of Adenovirus to Evade Neutralizing Antibodies.  Molecules; 23(10): 2565. doi:  [10.3390/molecules23102565]

 

Johnston,B.,  Radecka, I.,  Hill, D.; Chiellini, E., Ilieva,V.I.; Sikorska, W., Musioł, M.,  Zieba, M.,  Marek, A.A., Keddie, D., Mendrek, B.,  Darbar, S.,  Adamus, G. and Kowalczuk, M. (2018)  The Microbial Production of Polyhydroxyalkanoates from Waste Polystyrene Fragments Attained Using Oxidative Degradation.  Polymers. 2018, 10, 957; doi:10.3390/polym10090957.

 

Jiang , G., Johnston , B., Townrow , D., Radecka, I.,  Koller, M.,  Chaber , P., Adamus, G., Kowalczuk, M. (2018) Biomass extraction using non-chlorinated solvents for biocompatibility improvement of polyhydroxyalkanoates.  Polymers, 2018, 10, 731, doi: 10.3390/polym10070731,

 

Gonzalez-Ausejoa, J.,  Rydz, J.,  Musioł, M., Sikorska, W.,   Sobota, M., Włodarczyk, J.,  Adamus, G.,   Janeczek, H.,  Kwiecień, I.,  Hercog, A.,  Johnston, B.,  Khan, H., Kannappan, V.,  Jones, K., Morris, M.,  Jiang, G.,  Radecka, I.,  Kowalczuk, M. (2018)  A comparative study of three-dimensional printing directions:   The degradation and toxicological profile of a PLA/PHA. Polymer  Degradation and Stability, 152, 191-207

 

Kwiecień, I., Adamus, G.. Jiang, G., Radecka, I.,  Baldwin, T., Khan, H., Johnston, B., Pennetta, V., Hill, D., Bretz, I., Kowalczuk, M. (2017) Biodegradable PBAT/PLA blend with bioactive MCPA-PHBV conjugate suppresses weed growth.  Biomacromolecules, 19(2), 511

 

Johnston, B., Jiang, G., Hill, D., Adamus, G., Kwiecien, I., Zieba, M., Sikorska, W., Green, M., Kowalczuk, M. and Radecka, I.  (2017) The molecular level characterization of biodegradable polymers originated from polyethylene using non-oxygenated polyethylene wax as a carbon source for polyhydroxyalkanoate production. Bioengineering 2017, 4, 73; doi:10.3390/bioengineering4030073

 

Kwiecień, M., Radecka, I., Kowalczuk,  Jelonek,  K.,  Orchel, A ,  Adamus, G. (2017) The synthesis and structural characterization of graft copolymers composed of γ-PGA backbone and oligoesters pendant chains. Journal of The American Society for Mass Spectrometry. 2017 Oct;28(10):2223-2234. doi: 10.1007/s13361-017-1731-y

 

Kwiecień, M., Kwiecień, I., Radecka, I., Kannappan, V., Morris, MR,  Adamus, G. (2017) Biocompatible terpolyesters containing polyhydroxyalkanoate and sebacic acid structural segments – synthesis and characterization. RSC Advances, 2017, 7(33), S7751-S7761, doi: 0.1039/C6RA27980E. 

 

Musioł, M.,  Rydz, J.,  Janeczek, H., Radecka, I.,  Jiang, G. and  Kowalczuk, M. (2017)  Forensic engineering of advanced polymeric materials Part IV: Case study of oxo-biodegradable polyethylene commercial bag - Aging in biotic and abiotic environment. Waste Management, 2017, DOI: 10.1016/j.wasman.2017.03.043.

 

Khalil, IR.,  Irorere, VU.,  Radecka, I., Burns, ATH., Kowalczuk, M., Mason, JL., Khechara, M. (2017) Bacterial-Derived Polymer Poly-γ-Glutamic Acid  (γ-PGA)-Based Micro/Nanoparticles as a Delivery  System for Antimicrobials and Other Biomedical Applications. International  Journal of  Molecular Sciences , 2017, 18, 313; doi:10.3390/ijms18020313

               

Gupta, A.,  Low, W.L., Radecka, I.,  Britland, S.T.,  Amin, M.C.I. and Martin, C. (2016)  Characterisation and in vitro antimicrobial activity of biosynthetic silver-loaded bacterial cellulose hydrogels. Journal: Journal of Microencapsulation (IMNC) Article ID: IMNC 1253796, doi: 10.1080/02652048.2016.1253796  IF 1.531

 

Jiang, G., Hill, DJ., Kowalczuk, M., Johnston, B.,  Adamus, G., Irorere , V.,  Radecka, I. (2016) Carbon Sources for Polyhydroxyalkanoates and an Integrated Biorefinery. International  Journal of  Molecular Sciences 2016, 17, 1157; doi:10.3390/ijms17071157

 

Radecka, I., Irorere, V., Jiang, G., Hill, D., Williams, C., Adamus, G., Kwiecien,  M., Marek, AA., Zawadiak, J., Johnston, B., Kowalczuk, M. (2016) Oxidised Polyethylene Wax As A Potential Carbon Source For PHA Production. Materials,  2016, 9, 367; doi:10.3390/ma9050367

 

Kwiecień, I.,  Radecka, I.M., Kwiecień, M., Adamus, G.  (2016)  Synthesis and Structural Characterization of Bioactive PHA and γ-PGA Oligomers for Potential Applications as a Delivery System.  Materials  2016, 9, 307; doi:10.3390/ma9050307

 

Khalil, IR.,  Irorere, VU.,  Radecka, I., Burns, ATH., Kowalczuk, M., Mason, JL., Khechara, M. (2016) Poly-γ-Glutamic Acid: Biodegradable Polymer for Potential Protection of Beneficial Viruses.

Materials,  2016, 9, 28; doi:10.3390/ma9010028

 

Kwakye-Awuah,  B., Von-Kiti, E., Nkrumah, I., Erdoo Ikyreve, R., Radecka, I., Willimas, C.  (2016) Parametric, equilibrium, and kinetic study of the removal of salt ions from Ghanaian seawater by adsorption onto zeolite X. Desalination and Water Treatment, 1-14.  doi: 10.1080/19443994.2015.1128361

 

Kwiecień, I., Radecka,I.,  Kowalczuk, M.,  Adamus, G.  (2015) Transesterification of PHA to Oligomers Covalently Bonded with (Bio) Active Compounds Containing Either Carboxyl or Hydroxyl Functionalities.  PloS one 10 (3), 2015 doi:10.1371/journal.pone.0120149

 

Omowumi Ogunleye, A., Bhat, A., Irorere, V.U., Hill, D., Williams, C. and Radecka. I. (2015) Poly-gamma-glutamic acid - Production, Properties and Applications. Microbiology  (2015), 161, 1–17. doi 10.1099/mic.0.081448-0

 

Bhat, A., Irorere, V., Bartlett, T., D. Hill, D., Kedia, G., Charalampopoulos, D., Nualkaekul, S. and Radecka I. (2014) Improving survival of probiotic bacteria using bacterial Poly-γ-glutamic acid.

International Journal of Food Microbiology, doi: 10.1016/j.ijfoodmicro.2014.11.031

 

Brauer D.S., Karpukhina N., Kedia G., Bhat A., Law R.V. Radecka I., Hill R (2013) Bactericidal strontium-releasing injectable bone cements based on bioactive glasses. Journal of the Royal Society Interface  doi.10.1098/rsif.2012.0647, vol. 10 no. 78 20120647

 

Martin, C., Low WL., Amin MCIM., Radecka, I., Raj P and Kenward  K. (2013) Current trends in the development of wound dressings, biomaterials and devices Pharmaceutical Patent Analyst 2(3), pp.341-359. doi: 10.4155/ppa.13.18

 

Verlinden R. A. J., Hill D. J., Kenward M. A., Williams C. D. Piotrowska-Seget Z and  Radecka, I  (2011): Production of polyhydroxyalkanoates from waste frying oil by Cupriavidus necator. AMB Express.  1(1):11. doi: 10.1186/2191-0855-1-11.]

 

Kwakye-Awuah, B., Kenward, M.A., Williams C. and  Radecka, I. (2008)  Antimicrobial action and efficiency of silver-loaded zeolite X. Journal of Applied Microbiology  104, pp.1516-1524

 

 

Selected international conference publications:

 

Johnston, B., Hill, D., Kowalczuk, M., I. Kwiecień, I., Rydz, J., Jiang, G., Radecka, I. (2018) Polyhydroxyalkanoates (PHAs) Obtained From Waste Plastic Materials To Produce Biopolymers For Novel Applications. Institute of Macromolecular Chemistry. Czech Academy of Sciences. Careers in Polymers (Polymer X). June 22-23, 2018, Prague, Czech Republic.

 

Johnston, B., Hill, D., Kowalczuk, M., Jiang, G., Rydz, J., Gonzalez Ausejo, J and Radecka, I. (2018) Biopolymers for advanced medical applications based on polyhydroxyalkanoates (PHAs) derived from polyolefin waste materials. 4th International Conference on Biomedical Polymers & Polymeric Biomaterials. ISBPPB. July 15-18, 2018, Krakow, Poland

 

Gupta, A., Kowalczuk, M., Martin, C. and Radecka, I. (2018). “Biosynthetic Cellulose based hydrogels of Curcumin encapsulated in Cyclodextrins as wound dressings”,  4th International Conference on Biomedical Polymers & Polymeric Biomaterials. ISBPPB 15-18th July, Krakow, Poland.

 

Radecka, I., Johnston, B., Hill, D., Jiang, G. and Kowalczuk, M. (2018) Turning Plastic Waste into Added Value Materials. 11-13 June, 2018, Atlanta, USA.

 

Johnston, B., Hill, D., Kowalczuk, M., Jiang, G., I. Kwiecień, I., Rydz, J and Radecka, I. (2018) The production of polyhydroxyalkanoates (PHAs) from waste materials to produce biopolymers for novel environmental and medical applications. 3rd Green & Sustainable Chemistry Conference. May 13-16, 2018, Berlin, Germany.

 

Johnston, B., Hill, D., Kowalczuk, M., Jiang, G., Radecka, I. (2017) Alternative microbial carbon sources for the production of value-added bioplastics. DECHEMA Summer School 2017, September 11-15, 2017, Straubing, Germany

 

Radecka, I.  (2017)  King Midas approach – Turning waste plastic into valuable bioplastics. 9th European Symposium on Biopolymers: ESBP 2017, Toulouse, 5-7 Jul 17,2017

 

Radecka, I. Khalil, I., Hill, D., Kowalczuk, M., Burns, A., Khechara, M. (2017) Bacterial-Derived Gamma Polyglutamic Acid (γ-PGA) as a Protective Agent for Beneficial Viruses and its Potential Applications as a Smart Delivery System.  International conference: Nanomedicine and drug delivery. May 29-31, 2017, Osaka, Japan

 

Radecka, I. Khail, I., Hill, D., Kowalczuk, M., Burns, A., Khechara, M.(2017) Poly-gamma glutamic acid (γ-PGA ) - microbial polymer of commercial interest.  3rd Annual Conference,  International Society of Biomedical Polymers & Polymeric Biomaterials,  August 11 - 12, 2016, New Jersey, USA.

Richard Auta, Joshua Loh, Iza Radecka, and Paul Hooley (2015). Production of Bacterial Cellulose, Cloning and Characterization of Novel β-glucosidases from Gluconacetobacter xylinum. FASEB J. 29:573.1, Experimental Biology Conference, March 26 – April 1, 2015, Boston USA.

 

Adebayo O., Hill D., Radecka I. and Bartlett T. (2015). Enhanced production of bacterial cellulose and its application as a support carrier for B. breve and B. longum. Society for Applied Microbiology (SFAM) summer conference. 29th June-2nd July 2015, Dublin, Republic of Ireland.

 

Radecka I. (2014) Antimicrobial activity of silver zeolites and its applications. Workshop sponsored by Leverhulme – Royal Society African Award at the Kwame Nkrumah University of Science and Technology (KNUST). 22-29 April 2014 Kumasi, Ghana.

 

Ogunleye, A., Williams, C., Hill, D. and Radecka, I. (2014) Poly-gamma-glutamic acid (γ-PGA) – a promising biosorbent for removal of heavy metals. International Union of Microbiological Societies (IUMS) Congress, July 27 – August 1, 2014, Montreal, Canada,

 

Adamus, G., Kwiecień, I., Maksymiak, Radecka, I. and Kowalczuk, M. (2014) Novel synthetic approaches and opportunities for bioactive polyhydroxyalkanoates. International Society of Biomedical Polymers & Polymeric Biomaterials’ (ISBPPB) Annual Conference, July 9-12, 2014 Washington, D.C.  USA

 

Radecka I., (2013) Biodegradable plastics in the UK – past, present and future.  3rd PLASTiCE Conference ‘Future of Bioplastics’  COBRO,1-2 October 2013 Warsaw – Poland.

 

Radecka I. (2013) Antimicrobial activity of silver-loaded zeolite X. International Symposium on Ceramics and Nanotube Technology (ISCeNT), 6-9 March 2013, Nagoya, Japan.

 

Bhat, A., Kedia, G., Bartlett, T., Hill, D., Charalampopoulos, D., Radecka, I (2011). Making good bacteria happy!  4th Congress of European Microbiologists, June 26-30, 2011, Geneva, Switzerland

 

Bagheriasl,S; Radecka I, Jenkins M, Stamboulis A (2010)  Production and characterisation of polyhydroxybutyrate and its co-polymers from Ralstonia eutropha ISBP International Symposium on Biopolymers, Stuttgart

 

Radecka I. (2009) Production and characterization of bacterial poly- γ- glutamic acid “2nd International Conference from Nanoparticals & Nanomaterials to Nanodivices & Nanosystems. 28 June- 4July 2009, Rhodos, Greece.

 

Selected book/chapter publications:

 

Włodarczyk, J.,  Sikorska, W., Rydz, J.,  Johnston, B.,  Jiang,  G., Radecka, I., Kowalczuk, M. (2018) 3D processing of PHA  containing (bio)degradable materials, Chapter 6. In: Koller,  M.  (ed) Current advances in biopolymer processing & characterization. Biomaterials - properties, production and devices series, Nova Science Publishers, New York, US 2018. ISBN 9781536127102, pp. 121-168.

 

Iza Radecka, Guozhan Jiang, David Hill, Marek Kowalczuk (2015) Chapter 10 entitled: Polyhydroxyalkanoates composites and their applications in Green Polymer Composites Technology: Properties and Applications. Publisher: CRC Press Tylor & Francis Group. 163-176. Publication date November 2016. doi/abs/10.1201/9781315371184-11, Print ISBN: 978-1-4987-1546-1

 

Iza Radecka, Claire Martin, and David Hill (2014) Chapter 1 “The problem of microbial drug resistance” in Novel Antimicrobial Agents and Strategies. Publisher Wiley Eds., ISBN: 978-3-527-33638-8, October 2014 First Edition. 2015 Wiley-VCH Verlag GmbH & Co

 

Martin, C., Low, W. L., Gupta, A., Amin, M. C. I. M., Radecka, I., Britland, S. T., Raj, P. and Kenward, M.A. (2014). Chapter entitled: “Liposomal Delivery of Antimicrobials” in Advances in Liposome Research. Publisher: Nova Science Publishers, Inc.  ISBN: 9781631170775, 9781631170744