Dr Daniel J. Keddie is Senior Lecturer of Organic Chemistry in the School of Biology, Chemistry and Forensic Science at the University of Wolverhampton, UK. After completing both his BAppSc (hons) (2003) and PhD (2008) in synthetic organic/free radical chemistry at the Queensland University of Technology (QUT), Australia, he undertook postdoctoral research at the same institution in the area of silicone polymer synthesis. In 2009, he moved to the Commonwealth Scientific and Industrial Research Organization (CSIRO), Australia to undertake an OCE postdoctoral fellowship working with Dr Graeme Moad, co-inventor of the RAFT process. He remained at CSIRO until taking up a position as Lecturer of Organic Chemistry at the University of New England (UNE) in Armidale, Australia in late 2012, relinquishing this role in early 2015. He subsequently relocated to the UK and following a short appointment working on commercial research at the University of Warwick, UK, he took up his current position at Wolverhampton in July 2015. His research interests include the development of new methods in polymer synthesis, the characterization and application of novel polymeric materials and the design and synthesis of functional small molecules
Dr Keddie's research interests include: free radical chemistry; development of new methods in functional polymer synthesis; precision polymer synthesis (particularly RAFT and ROMP); transition metal catalysis; photochemistry; polymer self-assembly; characterization and application of complex polymeric materials (particularly towards biological systems and catalysis); high-throughput experimentation; silicon chemistry.
Member Chartered Chemist of the Royal Australian Chemical Institute (RACI) (Since 2001-)
Member of the American Chemical Society (ACS) (Since 2012-)
Member of the Materials Research Society (MRS) (Since 2013-)
1. R. Lyndon, K. Konstas, R. A. Evans, D. J. Keddie, M. R. Hill*, B. P. Ladewig*
Tunable Photodynamic Switching of DArE@PAF-1 for Carbon Capture,
Advanced Functional Materials, published online as an advanced article 22 June 2015, doi: 10.1002/adfm.201502069
2. G. Moad*, D. Keddie, C. Guerrero-Sanchez, E. Rizzardo, S. H. Thang
Advances in Switchable RAFT Polymerization,
Macromolecular Symposia, 350, 34-42 (2015)
3. J. Y.T. Chong, D. J. Keddie, A. Postma, X. Mulet, B. J. Boyd*, C. J. Drummond*
RAFT preparation and the aqueous self-assembly of amphiphilic poly(octadecyl acrylate)-block-poly(polyethylene glycol methyl ether acrylate) copolymers,
Colloids and Surfaces A: Physicochemical and Engineering Aspects, 470, 60-69 (2015)
4. J. Y.T. Chong, X. Mulet, D. J. Keddie, L. J. Waddington, S. T. Mudie, B. J. Boyd*, C. J. Drummond*
Novel steric stabilizers for lyotropic liquid crystalline nanoparticles: PEGylated-phytanyl copolymers, Langmuir, 31 (9), 2615–2629 (2014)
5. J. Y.T. Chong, X. Mulet, A. Postma, D. J. Keddie, L. J. Waddington, B. J. Boyd*, C. J. Drummond*
Novel RAFT amphiphilic brush copolymer steric stabilisers for cubosomes: Poly(octadecyl acrylate)-block-poly(polyethylene glycol methyl ether acrylate)
Soft Matter, 10 (35), 6666-6676 (2014).
6. J. J. Haven, C. Guerrero-Sanchez*, D. J. Keddie, G. Moad*, S. H. Thang, U. S. Schubert
One pot synthesis of higher order quasi-block copolymer libraries via sequential RAFT polymerization in an automated synthesizer
Polymer Chemistry, 5, 5236-5246 (2014).
7. D. J. Keddie*
A guide to the synthesis of block copolymers using reversible-addition fragmentation chain transfer (RAFT) polymerization
Chemical Society Reviews, 43, 496-505 (2014).
8. J. J. Haven, C. Guerrero-Sanchez*, D. J. Keddie, G. Moad*
Rapid and Systematic Access to Quasi-Diblock Copolymer Libraries Covering a Comprehensive Composition Range by Sequential RAFT Polymerization in an Automated Synthesizer
Macromolecular Rapid Communications, 35, (4), 492-497 (2013).
9. L. Sun, N. Petzetakis, A. Pitto-Barry, T. L. Schiller, N. Kirby, D. J. Keddie, B. J. Boyd, R. K. O’Reilly*, A. P. Dove*
Tuning the Size of Cylindrical Micelles from Poly(l-lactide)-b-poly(acrylic acid) Diblock Copolymers Based on Crystallization-Driven Self-Assembly
Macromolecules, 46, 9074-9082 (2013).
10. D. J. Keddie*, C. Guerrero-Sanchez, G. Moad*
The reactivity of N-vinylcarbazole in RAFT polymerization: trithiocarbonates deliver optimal control for the synthesis of homopolymers and block copolymers
Polymer Chemistry, 4, 3591-3601 (2013).
11. C. Guerrero-Sanchez*, L. O’Brien, C. Brackley, D. J. Keddie, S. Saubern, J. Chiefari
Quasi-Block Copolymer Libraries on Demand via Sequential RAFT Polymerization in an Automated Parallel Synthesizer
Polymer Chemistry, 4, 1857-1862 (2013).
12. C. Guerrero-Sanchez*, S. Harrisson, D. J. Keddie
High-Throughput Method for RAFT Kinetic Investigations and Estimation of Reactivity Ratios in Copolymerization Systems
Macromolecular Symposia, 325-326, 38-46. (2013)
13. C. Guerrero-Sanchez*, D. J. Keddie, S. Saubern, J. Chiefari
Automated Parallel Freeze-Thaw Degassing Method for Oxygen-Sensitive Reactions: RAFT Polymerization
ACS Combinatorial Science, 14, 389-394 (2012).
14. D. J. Keddie, G. Moad*, E. Rizzardo, S. H. Thang
RAFT Agent Design and Synthesis
Macromolecules, 45, 5321-5342 (2012).
15. D. J. Keddie*, C. Guerrero-Sanchez, G. Moad*, R. J. Mulder, E. Rizzardo, S. H. Thang
Chain Transfer Kinetics of Acid/Base Switchable N-Aryl-N-Pyridyl Dithiocarbamate RAFT Agents in Methyl Acrylate, N-Vinylcarbazole and Vinyl Acetate Polymerization
Macromolecules, 45, 4205-4215, (2012).
16. S. Houshyar, D. J. Keddie, G. Moad*, R. J. Mulder, S. Saubern, J. Tsanaktsidis
The scope for synthesis of Macro-RAFT Agents by Sequential Insertion of Single Monomer Units
Polymer Chemistry, 3, 1879-1889 (2012).
17. B. L. Furrugia, D. J. Keddie, G. A. George, E. C. Lynam, M. A. Brook, Z. Upton, T. R. Dargaville*
An Investigation into the Effect of Amphiphilic Siloxane Oligomers on Dermal Fibroblasts
Journal of Biomedical Materials Research: Part A, 100A (7), 1919-1927 (2012).
18. D. J. Keddie, J. B. Grande, F. Gonzaga, M. A. Brook*, T. R. Dargaville*
Amphiphilic Silicone Architectures via Anaerobic Thiol–Ene Chemistry
Organic Letters. 13 (22), 6006-6009 (2011).
19. D. J. Keddie*, C. Guerrero-Sanchez, G. Moad*, E. Rizzardo, S. H. Thang
Switchable Reversible Addition-Fragmentation Chain Transfer (RAFT) Polymerization in Aqueous Solution, N,N-Dimethylacrylamide
Macromolecules, 44 (17), 6738-6745 (2011).
20. B. J. Morrow, D. J. Keddie, N. Gueven, M. F. Lavin, S. E. Bottle*
A Novel Profluorescent Nitroxide as a Sensitive Probe for the Cellular Redox Environment
Free Radical Biology and Medicine, 49 (1), 67-76. (2010).
21. M. A. Lam, D. I. Pattison, S. E. Bottle, D. J. Keddie, M. J. Davies*
Nitric Oxide and Nitroxides Can Act as Efficient Scavengers of Protein-Derived Free Radicals
Chemical Research in Toxicology, 21(11), 2111-2119 (2008).
22. J. P. Blinco, D. J. Keddie, T. Wade, P. J. Barker, G. A. George, S. E. Bottle*
Profluorescent Nitroxides: Sensors and Stabilizers of Radical-Mediated Oxidative Damage
Polymer Degradation and Stability, 93 (9), 1613-1618 (2008).
23. D. J. Keddie, K. E. Fairfull-Smith, S. E. Bottle*
The Palladium-Catalyzed Copper-Free Sonogashira Coupling of Isoindoline Nitroxides: A Convenient Route to Robust Profluorescent Carbon-Carbon Frameworks
Organic & Biomolecular Chemistry. 6 (17), 3135-3143 (2008).
24. K. E. Fairfull-Smith, J. P. Blinco, D. J. Keddie, G. A. George, S. E. Bottle*
A Novel Profluorescent Dinitroxide for Imaging Polypropylene Degradation
Macromolecules, 41(5), 1577-1580 (2008).
25. D. J. Keddie, S. E. Bottle, J. K. Clegg, J. C. McMurtrie* (2006)
Acta Crystallographica, Section E: Structure Reports Online, E62 (8), o3535-o3536 (2006).
26. D. J. Keddie, T. E. Johnson, D. P. Arnold, S. E. Bottle*
Synthesis of Profluorescent Isoindoline Nitroxides via Palladium-Catalyzed Heck Alkenylation
Organic & Biomolecular Chemistry, 3(14), 2593-2598 (2005).