Dave graduated in microbiology and subsequently studied for a PhD in the ‘Regulation of enzyme levels in methylotrophic Candida spp’ at University of Wales, College Cardiff. This led to postdoctoral research at Leeds University involving the protein engineering of yeast alcohol oxidases.
Upon arrival at the University of Wolverhampton in the 1980s consultancy interests were developed in biodegradation and subsequently research into the control of intestinal bacterial pathogens in the environment, intestinal tract, and food industry. More recently he has expanded his interest in environmental microbiology and the development of biopolymers with Dr Radecka. Over the years he has established numerous links with local and national companies providing consultancy and research support in a variety of microbiological aspects.
In addition to research and consultancy, various aspects of microbiology are taught on a range of courses at undergraduate and master’s levels.
Dave's main interests are :
• The growth, survival and control of gastrointestinal (GI) pathogens (eg Campylobacter , Salmonella, E.coli, Listeria, Helicobacter) in aquatic systems, foods, surfaces, and in the GI tract
• The roles of microorganisms in pollution control.
This has involved research and collaborations including:
• Antimicrobial plant extracts (especially essential oils of herbs and spices) – effect upon gastrointestinal bacteria; control of food spoilage; factors affecting efficacy (including synergy with other antimicrobial agents and environmental factors)
• Microbial attachment to surfaces, formation of biofilms and factors affecting subsequent cleaning and disinfection
• Development of antimicrobial coatings / surfaces – incorporation of antimicrobials into polymers and subsequent evaluation
• Bacterial synthesis of poly-gamma-glutamic acid (γ-PGA) and its environmental application.
• Bioremediation of petroleum hydrocarbons in contaminated soils
Dave is currently involved in the supervision of three PhD students and 2 Knowledge Transfer Associates
Member of the Society for Applied Microbiology
Recent publications include :
Radecka, I., Jiang, G., Hill, D., & Kowalczuc, M. (2015). Polyhydroxyalkanoates composites and their applications. Publisher: CRC Press
Ogunleye, A. O., Bhat, A., Hill, D.J., Williams, C. & Radecka, I. (2015). Poly-[gamma]-glutamic acid - Production, Properties and Applications. Microbiology (in press)
Bhat, A., Irorere, V.U., Mistry, N., Bartlett, T., Hill, D., Kedia, G., Charalampopoulos, D. & Radecka, I. (2015). Improving survival of probiotic bacteria using bacterial Poly-γ-glutamic acid. International Journal of Food Microbiology 196, 24-31
Radecka, I., Martin, C. & Hill, D. (2014) - The Problem of Microbial Drug Resistance. Chapter 1 in ‘Novel Antimicrobial Agents and Strategies’. Publisher: Wiley Eds. Phoenix, D.A., Harris, F., & Dennison, S.R.. Publisher: Wiley-VCH Verlag GmbH & Co. KGaA.
Low, W-L., Lee, C., Wilkes, M., Roberts, C. & Hill, D.J., 2014. ‘Development of a rapid, effective method for seeding biofiltration systems using alginate bead-immobilised cells’. Int. J. Chem. & Env. Eng., vol. 5 (1) pp29-32. ISSN 2078-0737
Bhat, A., Irorere, V.U., Bartlett, T., Hill, D., Kedia, G. Morris, M., Charalampopoulos, D., and Radecka, I. (2013). Bacillus subtilis natto: a non-toxic source of poly-γ-glutamic acid that could be used as a cryoprotectant for probiotic bacteria. AMB Express 3:36, ISSN: 2191-0855
Low, W.L., Martin, C., Hill, D.J. & Kenward, M.A. (2013). Antimicrobial Efficacy of Liposome Encapsulated Silver Ions and Tea Tree Oil against Pseudomonas aeruginosa, Staphylococcus aureus and Candida albicans. Letters in Applied Microbiology 57 (1), pp33-39. . ISSN: 0266-8254
Bhat, A., Kedia, G., Bartlett, T., Hill, D., & Radecka I (2012):UK Patent Application No: 1115143.8. ‘Improved viability of Probiotic Micro-organisms’Short Title: Probiotic Bacteria (BB ref: TG59959P.GBA-LPT).
Hall, S., Gibson, H., Lambert, A.M., and Hill, D.J. (2011). Bioaerosol Monitoring – a Practical Evaluation. 16th European Biosolids & Organic Resources Conference Proceedings 14th-16thth November, Leeds.
Verlinden,R.A.J, Hill, D.J., Kenward, M.A., Williams, C.D. & Radecka, I (2011). Production of polyhydroxyalkanoates from waste frying oil by Cupriavidus necator (PHAs from waste oil by C. necator). AMB Express 1:11, 1-8.
Low, W.L., Martin, C., Hill, D.J. & Kenward, M.A. (2011). Antimicrobial Efficacy of Silver Ions in Combination with Tea Tree Oil Against Pseudomonas aeruginosa, Staphylococcus aureus and Candida albicans. International Journal of Antimicrobial Agents, 37, 162-165.
Bhat, A., Kedia, G., Bartlett, T., Hill, D., Charalampopoulos, D., Radecka I (2010): Investigation of Poly-γ-glutamic Acid Production From Six Different Bacillus Strains. IBS2010 14th International Biotechnology Symposium and Exhibition Biotechnology for the Sustainability of Human Society ,14-18 September 2010, Palacongressi, Rimini – Italy. DOI 10.1016/j.jbiotec.2010.09.598. Abstract 229 published in conference proceedings Journal of Biotechnology.
Angienda, P.O. & Hill, D.J. (2010). The Effect of Sodium Chloride and pH on the Antimicrobial Effectiveness of Essential Oils against Pathogenic and Food Spoilage Bacteria: Implications in Food Safety. International Journal of Medicine and Medical Sciences, 1 (4), 222-227
Kedia, G., Hill, D.J., Hill, R. and Radecka, I. (2010). Production of poly-g-glutamic acid by Bacillus subtilis and Bacillus licheniformis with different growth media. Journal of Nanoscience & Nanotechnology, 10, 1-9.
Rowe, C. L., Hill, D. J. Williams, C. D. and Owen, J. P. (2008). Evaluation of a novel technology for the bioremediation of hydrocarbon contaminated materials. Poster presentation and published in conference proceedings [ID 38]. 4th European Bioremediation conference in Chania, Crete, Greece.
Kedia G., Hill, D. and Radecka I. (2008): Synthesis of Poly-γ-glutamic acid by Bacillus licheniformis and Bacillus subtilis. At III International Seminar on Biodegradable Polymers 2008, Valencia, 3rd and 4th March 2008, conference proceeding
Walton, J.T., Hill, D.J., Protheroe, R.G., Nevill, A. and Gibson, H. (2008). Investigation into the effects of detergents on disinfectant susceptibility of attached E. coli and L. monocytogenes. Journal of Applied Microbiology, 105, 309-315.
O’Gara, E. A., Maslin, D. J. and Hill, D. J. (2008) The Effect of Simulated Gastric Environments on the Anti-Helicobacter activity of Garlic Oil. Journal of Applied Microbiology 104, 1324-1331