Name Dr Paul Hooley
Job Title Senior Lecturer in Cell and Molecular Biology
Faculty Faculty of Science and Engineering
School School of Sciences
Subject(s) Biology, Chemistry and Forensic Science
Tel 01902 323492

Biology, Chemistry and Forensic Science

Paul graduated from the University of Liverpool in 1980 with a first class honours degree in Botany.  This was followed by a period as a Research Assistant in the Environmental Advisory Unit also at the University of Liverpool.  Postgraduate research on ‘The Genetics ofPhytophthora’ led to the award of a PhD from the University of Wales, Bangor in 1984. Paul took a P.G.C.E at the University of Liverpool and was then appointed as a Postdoctoral Research Fellow at Liverpool Polytechnic working on the manipulation of Streptomyceshygroscopicus for production of herbicidal antibiotics. He was North West Cancer Research Fellow 1985 – 1988, looking at DNA damage and repair in Aspergillus nidulans and Postdoctoral Senior Research Assistant 1988 - 1990 in the  Department of Genetics, University of Liverpool working on the molecular characterisation of mammalian and fungal GATA transcription factors.

Paul’s current research interests include the molecular basis of stress tolerance in eukaryotes, the biotechnology of hydrophobins and the engineering of cellulose degrading enzymes.  He was an Associate Editor of Mycological Research (2003 –2009), Honorary Senior Research Fellow at the University of Birmingham (2010 – 2013) and has been awarded a Senior Fellowship of the Higher Education Academy (2014).

  • DNA repair, molecular biology of fungi, stress responses in eukaryotes, biotechnology of hydrophobins, polyphosphate kinases, beta glucosidases and biofuels.
  • DNA repair, molecular biology of fungi, stress responses in eukaryotes, biotechnology of hydrophobins, polyphosphate kinases, beta glucosidases and biofuels.

Recent publications

Whitehead M.P., Eagles L., Hooley P. and M.R.W. Brown (2014) Most bacteria synthesise polyphosphate by unknown mechanisms. Microbiology 160 829-831.

Green A., Littlejohn, K., Hooley P. and Cox P.W. (2013) Formation and stability of food foams and aerated emulsions. Hydrophobins as novel functional ingredients. Current Opinion in Colloid and Interface Science 18 292 - 301.

Whitehead M.P., Hooley P. and Brown M.R.W. (2013) Horizontal transfer of bacterial polyphosphate kinases to eukaryotes : implications for the ice age and land colonisation. BMC Research Notes 6 : 221, 1 – 12 doi:10.1186/1756-0500-6-221.

Littlejohn, K., Hooley P. and Cox P.W. (2012) Bioinformatics predicts diverse Aspergillus hydrophobins with novel properties. Food Hydrocolloids 27 503 - 516.

Freimanis G., Hooley P., Davari Ejtehadi H., Ali H.A., Veitch A., Rylance P.B., Alawi A., Axford J., Nevill A., Murray P.G., Nelson P.N. (2010) A role for human endogenous retrovirus-K (HML-2) in rheumatoid arthritis: investigating mechanisms of pathogenesis. Clinical and Experimental Immunology 160 340 - 347.

Dibra H.K., Brown J.E., Hooley P. and I.D. Nicholl (2010) Aspirin and alterations in DNA repair proteins in the SW480 colorectal cancer cell line. Oncology Reports 24 37 – 46.

Cox P. and Hooley P. (2009) Hydrophobins – new prospects for biotechnology. Fungal Biology Reviews 23 40 -47.

Chilton I.J., Delaney C.E., Barham-Morris J., Fincham D.A., Hooley P., and Whitehead M.P. (2008) The Aspergillus nidulans stress response transcription factor StzA is ascomycete - specific and shows species - specific polymorphisms in the C - terminal region. Mycological Research 112 1435 - 1446.

Hooley P., Whitehead M.P. and M.R.W. Brown (2008) Eukaryote polyphosphate kinases – is the “Kornberg” complex ubiquitous? Trends in Biochemical Sciences 33 577 – 582.