This is an exchange-based programme to enable the development of biomarker-functionalized vehicles. It aims at the transfer of technologically advanced methods for the synthesis of pharmaceutical materials, for targeted drug delivery, and for cancer cell imaging and treatment. The exchange programme comprises two EU partners (University of Wolverhampton, UK and University of Navarra, Spain), one Chinese partner (Sichuan University, China), and one American Partner (Florida International University, USA), many of whom are centres of excellence.
The exchange programme comprises 50 person-months, over four years, and aims to achieve a foundation for both scientific and strategic development leading to long-lasting scientific collaboration between the European Union, China and the USA.
Scientific novelty lies in the use of synthesised multi-functional nano-processed matrices. Both cancer cell-targeted probes, and anti-cancer drugs, will be formulated in appropriate dosage forms for cancer cell imaging and treatment. Building these functionalised vehicles, and evaluating them in vitro, requires a combination of expertise not available at a single centre.
The work is organised into definite, but complimentary, work-packages (WPs) that will be executed by the combined effort of the four partners. Each WP has will require, on average, 12 person-months of input (range 2 to 24 person-months) depending on technical input and the funding stages in the programme. On completion of this project, each partner will have acquired valuable new knowledge, skills and expertise resulting in the potential for further new innovations in cancer diagnosis and treatment. Such expertise may then be transferred to industry, and will strengthen EU-Chinese collaboration in order to close existing gap with USA and Japan.