Name Dr Wan Li Low
Job Title Lecturer in Pharmacy Science
Faculty Faculty of Science and Engineering
School School of Pharmacy
Subject(s) Pharmacy, Pharmaceutical Science, Microbiology
Tel 01902 32 2178
Email W.L.Low2@wlv.ac.uk

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Dr. Wan Li Low (BSc. (Hons), PhD, CBiol, MRSB, MAPS), is an experienced scientist, capable of delivering high quality teaching and research with a wide range of knowledge and expertise spanning the interdisciplinary fields of pharmaceutical sciences, formulation aspects of antimicrobial drug delivery, microbiology, biotechnology and biology. Upon completing her PhD in liposomal delivery of antimicrobial metal ions and essential oils, she was appointed as a Process Development Scientist as part of a Knowledge Transfer Partnership (KTP) programme between OSIL Ltd. and the University of Wolverhampton. Dr. Low demonstrated excellent qualities to bridge scientific knowledge and research with appropriate business acumen, which resulted in successful project outcomes combined with a prestigious award as the “Business Leader of Tomorrow 2013”. The project was a great success and the Technology Strategy Board awarded additional funding to extend the project, as well as an “Excellent” project grade for its outstanding impact on both the business and the university. Dr. Low continued her research career as a post-doctoral fellow with the Anti-Infective Delivery Research Group (AIDRG) within the School of Pharmacy at the University of Wolverhampton. Her research within AIDRG focuses on the development of smart, responsive controlled release delivery systems to deliver alternative non-antibiotic antimicrobial agents for the management of chronic wound infections. Dr. Low’s contribution to research in biological sciences has been recognised by the Royal Society of Biology with the award of Chartered Biologist (CBiol) status. As Lecturer in Pharmacy Science, Dr. Low is currently contributing to teaching and research activities on the MPharm, BSc. (Hons) Pharmaceutical Science and MSc. degree courses within the School of Pharmacy.

Natural antimicrobial products (essential oils and metal ions)

Antimicrobial studies

Formulation and delivery of antimicrobial agents

Wound management

  • Antimicrobial activity of essential oils (e.g. tea tree oil) and metal ions (e.g. silver)
  • Development of preparations combining tea tree oil with silver for application in wound healing
  • Controlled delivery of antimicrobial agents using a variety of drug delivery systems e.g. liposome encapsulation and hydrogel formulations
  • Creation of a wound management devices that enhance wound healing, reduces the frequency of dressing changes and minimizes impact of antimicrobial agents on healthy tissue and the environment
  • In vitromodelling of the wound healing process
  • Formulation of responsive, controlled release delivery systems for wound management
  • Formulation and assay development of novel antimicrobial agents

Member of the Academy of Pharmaceutical Sciences, U.K. (MAPs)

Member of the Royal Society of Biology, U.K. (MRSB) and Chartered Biologist (CBiol)

Member of Microbiology Society, U.K.

Member of Society for Applied Microbiology, U.K.

Selected publications (original articles, review articles, book chapters and peer reviewed conference proceedings):

 

2016

Low, W.L., Kenward, M.A., Britland, S.T., Amin, M.C.I.M. and Martin, C. (2016). Essential oils and metal ions as alternative antimicrobial agents: a focus on tea tree oil and silver. International Wound Journal. DOI: 10.1111/iwj.12611.

Low, W.L., Kenward, M.A. and Martin, C. (2016). Ionically crosslinked chitosan hydrogels for the controlled release delivery of antimicrobial essential oils and metal ions.  Medicines, 3(1): 8; DOI:10.3390/medicines3010008.

Low, W.L., Martin, C., Hill, D.J. and Kenward, M.A. (2016) Characterisation and in vitro Antimicrobial Potential of Liposomal Silver Ions against Candida albicans.  Journal of Microencapsulation, 33(2): 146-152.

Gupta, A., Britland, S.T., Radecka, I., Low, W.L. and Martin, C. (2016).  Development of biosynthetic cellulose hydrogels loaded with antimicrobial silver nanoparticles for wound dressing applications.  UKPharmSci 2016 Conference Proceedings, 5th – 7thSeptember 2016, Technology & Innovation Centre, University of Strathclyde, Glasgow, U.K. 

 

2015

Martin, C., Low, W.L., Gupta, A., Amin, M.C.I.M., Radecka, I., Britland, S.T., Raj, P. and Kenward, M.A. (2015).  Strategies for Antimicrobial Drug Delivery to the Biofilm.  Current Pharmaceutical Design, 21 (1): 43-66. 

Dosanjh, P.K., Low, W.L., Radecka, I., Britland, S.T. and Martin, C. (2015).  Liposomal silver nitrate embedded within a bacterial cellulose hydrogel:  Antimicrobial activity against Pseudomonas aeruginosa and Staphylococcus aureus.  Liposome Advances 2015 Conference Proceedings, 19th – 22nd December 2015, UCL School of Pharmacy, University of London, London, U.K.

 

2014

Martin, C., Low, W.L., Gupta, A., Amin, M.C.I.M., Radecka, I., Britland, S.T., Raj, P., and Kenward, M.A. (2014).  “Liposomal Delivery of Antimicrobials” in Advances in Liposome Research (part of the Biochemistry Research Trends series) edited by Laura Finney.  Nova Science Publishers Inc., New York.  ISBN 978-1-63117-074-4: pp. 27-62.

Low, W.L., Lee, C., Wilkes, M., Roberts, C. and Hill, D.J. (2014). Development of a rapid, effective method for seeding biofiltration systems using alginate bead-immobilized cells. International Journal of Chemical and Environmental Engineering. 5(1): 29-32.

Low, W.L., Hill, D.J., Roberts, C., Wilkes, M., Lee, C. (2014). Odour Control - Developing New Strategies. Proceedings of the 19th European Biosolids & Organic Resources Conference. Edited by Horan, N.J. Aqua Enviro, 18th-19th November 2014, Manchester Town Hall, Manchester, U.K.

Low, W.L., Lee, C., Wilkes, M., Roberts, C. and Hill, D.J. (2014). Packing material in biofiltration systems: Woodchip vs. Pumice. NOSE 2014 Conference Proceedings, 14th-17th September 2014, Fondazione Querini Stampalia, Venice, Italy.

 

2013

Low, W.L., Martin, C., Hill, D.J. and Kenward, M.A. (2013).  Antimicrobial Efficacy of Liposome Encapsulated Silver Ions and Tea Tree Oil Against Pseudomonas aeruginosa, Staphylococcus aureus and Candida albicans.  Letters in Applied Microbiology, 57 (1): 33-39.

Martin, C., Low, W.L., Amin, M.C.I.M., Radecka, I., Raj, P. and Kenward, M.A. (2013).  Current trends in the development of wound dressings, biomaterials and devices.  Pharmaceutical Patent Analyst, 2 (3): 341-359.

 

2011

Low, W.L., Martin, C., Hill, D.J. and Kenward, M.A. (2011).  Antimicrobial Efficacy of Silver Ions in Combination with Tea Tree Oil Against Pseudomonas aeruginosa, Staphylococcus aureus and Candida albicans.  International Journal of Antimicrobial Agents, 37 (2): 162-165.

Kainth, J.S., Grewal, A.S., Greenwood, S., Low, W.L., Kenward, M.A. and Martin, C. (2011).  Controlled Release Chitosan Hydrogels for Delivery of Antimicrobials: I. Formation and Stability.  UKPharmSci 2011 Conference Proceedings, 31st August – 2nd September 2011, East Midlands Conference Centre, University of Nottingham, Nottingham, U.K.

Kainth, J.S., Grewal, A.S., Greenwood, S., Low, W.L., Kenward, M.A. and Martin, C. (2011).  Controlled Release Chitosan Hydrogels for Delivery of Antimicrobials: II. Drug Release and Antimicrobial Activity.  UKPharmSci 2011 Conference Proceedings, 31st August – 2nd September 2011, East Midlands Conference Centre, University of Nottingham, Nottingham, U.K.

Low, W.L., Martin, C. and Kenward, M.A. (2011).  Development of Antimicrobial Liposome Encapsulated Tea Tree Oil (TTO) and Silver Ions (Ag+) for Topical Wound Management.  UKPharmSci 2011 Conference Proceedings, 31st August – 2nd September 2011, East Midlands Conference Centre, University of Nottingham, Nottingham, U.K.

 

2010

Low, W.L., Martin, C. and Kenward, M.A. (2010).  Antimicrobial Activity of Zeolite Exchanged and Liposome Encapsulated Silver Ions.  Proceedings of the International Symposium of Controlled Release and Bioactive Materials, 37 (2010).  #18.

Low, W.L., Martin, C. and Kenward, M.A. (2010).  Approaches to controlled release of antimicrobial tea tree oil (TTO) and silver ions (Ag+) by liposome encapsulation.  Journal of Pharmacy and Pharmacology, 62 (10): 1250 – 1251. 

Rasul, N., Dosanjh, P.K., Hashmi, I., Abass, K., Riasat, U.A., Low, W.L., Kenward, M.A. and Martin, C. (2010).  Ionically Crosslinked Chitosan Hydrogels for Controlled Release of Antibiotics.  Proceedings of the International Symposium of Controlled Release and Bioactive Materials, 37 (2010).  #723.

 

2009

Low, W.L., Kenward, M.A. and Martin, C. (2009).  Antimicrobial Effect of Tea Tree Oil and Silver: Potential Enhancement with Liposomal Encapsulation.  Journal of Pharmacy and Pharmacology, 61: A-90, #122.

Low, W. L., Martin, C. and Kenward, M.A. ‘Ken’ (2009).  A comparison of antimicrobial efficacy of free and liposome encapsulated tea tree oil (TTO) and silver (AgNO3) both singly and in combination. Society for General Microbiology (SGM) Spring Meeting Harrogate International Centre 30 March–2 April 2009.  Abstract number HAR2/04: 42.