Name Dr Chris Perry
Job Title Senior Lecturer (Organic and Pharmaceutical Chemistry)
Faculty Faculty of Science and Engineering
School School of Pharmacy
Subject(s) Pharmacy
Research Group Cancer Research
Tel 01902 322152
Email c.j.perry@wlv.ac.uk

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Chris has been teaching in Further and Higher Education for over twenty years and is also an Associate Lecturer with the Open University. He has been an External Examiner for more than ten years in five different UK Universities. 

In the mid 1980s he was a Research Chemist for Allied Colloids in West Yorkshire before moving into education. 

During the 1990s he received funding to the value of £180K for a total of three Teaching Company Associates.  These projects resulted in significant development of chemical-based products for two West Midlands companies.

Synthesis of and modelling chemical reactivity in heterocyclic compounds.

Chris’s research interests are centred around the synthesis and characterisation of small molecules that have potential in the treatment of cancer. In particular, he is currently working on a library of rare and novel salicylate compounds which are able to suppress the growth of colorectal and other cancer cells. In conjunction with Dr Iain Nicholl, these molecules are now being tested at Wolverhampton and in a number of collaborating centres including Edinburgh, Central Lancashire and Aston Universities.

Current research projects

  • Simple methods for the production of expensive and rare salicylate esters
  • Evaluation of a wide range of salicylate analogues for their anti-cancer and pharmacokinetic properties
  • Investigation of the composition of Gum Arabic (collaboration with Dr Tim Baldwin & Prof Pete Williams)

 

Select publications

  • Grewall, N., Parveen, Z., Large, A.T., Perry, C.J. and Connock, M.J. (2000) Gastropod mollusc aliphatic alcohol oxidase:subcellular localisation and properties. Comparative Biochemistry and Physiology Part B, 125, pp.543-554.
  • Parveen, Z., Large, A., Grewal, N., Lata, N., Cancio, I., Cajaraville, M.P., Perry, C.J. and Connock, M.J. (2001) D-Aspartate oxidase and D-amino acid oxidase are localised in the peroxisomes of terrestrial gastropods. European Journal Of Cell Biology, 80(10), pp.651-660.
  • Perry, C.J. and Parveen, Z. (2001) The cyclisation of substituted phthalamic acids. A study of N-phenylphthalimide formation. J. Chem. Soc. Perkin Trans., 2, pp.512-521.
  • Knigge, T., Mann, N., Parveen, Z., Perry, C.J., Gernhöffer, M., Triebskorn, R., Köhler, H.R. and Connock,  M.J. (2002) Mannosomes: a molluscan intracellular tubular membrane system related to heavy-metal stress. Comp. Biochem. and Physiol., (Part C 131), p.259.
  • Perry, C.J., Holding, K. and Tyrrell, E. A simple synthesis for N-carbamoylbenzotriazole and some of its analogues. Synthetic Communications, 38(19), pp3354-3365, 2008.
  • J. Deb, H. Dibra, S. Shan, S. Rajan, J. Manneh, C.S. Kankipati, C.J. Perry and I. D. Nicholl, Activity of aspirin analogues and vanillin in a human colorectal cancer cell line. Oncology Reports 26: 557-565, 2011.
  • M. Chua, K Chan, T.J. Hocking, P. A. Williams, C.J. Perry, T.C. Baldwin, Methodologies for the extraction and analysis of konjac glucomannan from corms of Amorphophallus konjac K. Koch. Carbohydrate Polymers 87: 2202– 2210, 2012.
  • Perry, C.J., Holding, K. and Tyrrell, E.  A simple synthesis for N-carbamoylbenzotriazole and some of its analogues. Synthetic Communications, 38(19), pp3354-3365, 2008.
  • J. Deb, H. Dibra, S. Shan, S. Rajan, J. Manneh, C.S. Kankipati, C.J. Perry and I. D. Nicholl, Activity of aspirin analogues and vanillin in a human colorectal cancer cell line. Oncology Reports 26: 557-565, 2011.
  • M. Chua, K Chan, T.J. Hocking, P. A. Williams, C.J. Perry, T.C. Baldwin, Methodologies for the extraction and analysis of konjac glucomannan from corms of Amorphophallus konjac K. Koch. Carbohydrate Polymers 87: 2202– 2210, 2012.