Name Dr Mark Morris
Job Title Reader in Molecular Oncology
Faculty Faculty of Science and Engineering
School School of Sciences
Subject(s) Biology, Chemistry and Forensic Science
Tel 01902 322574
Email M.R.Morris2@wlv.ac.uk

Biology, Chemistry and Forensic Science

Dr Mark Morris leads a research group within the Research Institute In Healthcare Science (RHIS) investigating the molecular biology and genetics of cancer development.                    

Mark gained his PhD in 2001 following a period of research (at the University of Wales College of Medicine) into the regulation of proliferative life-span barriers in human tumours.

Prior to joining the University of Wolverhampton, in 2010, Mark investigated the molecular basis of cancer and developmental diseases with a particulate interest in epigenetic gene dysregulation as a mechanism that drives tumour formation. This research was carried out at the Department of Medical Genetics, University of Birmingham, where he currently holds the post of Honorary Lecturer in Molecular Oncology. His teaching includes general biochemistry, cell biology, and molecular genetics, particularly related to human disease. 

  

Research

         Mark is currently investigating:

  • The role of epigenetic gene dysregulation in the process of tumour formation and metastasis.
  • The role epigenetics (in particular DNA methylation and microRNAs) play in the development of childhood cancers of the brain and the kidney.
  • RNA-processing in tumour development.
  • The identification of new therapeutics against cancer.

Research Collaborators

  • Professor Eamonn Maher: Department of Medical Genetics, University of Cambridge
  • Professor Farida Latif: The Centre for Rare Diseases and Personalised Medicine, University of Birmingham.
  • Dr Emma Woodward: School of Clinical and Experimental Medicine, University of Birmingham.
  • Dr Boris Kysela: School of Clinical and Experimental Medicine, University of Birmingham.
  • Dr Tracy Warr: Department of Neuro-oncology, University of Wolverhampton.
  • Dr Raul Sutton: Department of Forensic and Molecular biosciences, University of Wolverhampton.
  • Professor Tim Dawson: Department of Neuropathology, Lancashire Teaching Hospitals.
  • Professor Charles Davies: Department of Neurosurgery, Lancashire Teaching Hospitals.
  • Dr Carole Walker: Walton Centre for Neurology and Neurosurgery, Liverpool.

Selected Publications

Book Chapters

Urological Oncology 2nd edition 2014
Chapter 3:  Genetics and Genito-Urinary Cancer
Eds: Nargund, Vinod H.; Raghavan, Derek; Sandler, Howard M.
Publisher: Springer
ISBN: 0857294814

Future Projects

  • Genetic and epigenetic dysregulation in tumour evolution and distant site metastasis.
  • Genetics and epigenetics of childhood cancers.
  • The role of exosome dysregulated RNA processing in tumour formation.
  • Targeted DNA de-methylation as cancer therapy.

If you are interesting in studying any of these subject areas at doctoral level please contact Mark on the contact details above.